Characterization of a novel Neisseria gonorrhoeae penicillinase-producing plasmid isolated in Australia in 2012.
نویسندگان
چکیده
Ella Trembizki, Cameron Buckley, Andrew Lawrence, Monica Lahra, David Whiley, on behalf of the GRAND Study Investigators Queensland Paediatric Infectious Diseases Laboratory, Queensland Children’s Health Services, Brisbane, Queensland, Australia; Queensland Children’s Medical Research Institute, The University of Queensland, Brisbane, Queensland, Australia; Microbiology and Infectious Diseases Directorate, SA Pathology, Adelaide, South Australia, Australia; WHO Collaborating Centre for STD, Microbiology Department, South Eastern Area Laboratory Services, Prince of Wales Hospital, Sydney, New South Wales, Australia
منابع مشابه
Penicillinase-producing Neisseria gonorrhoeae in the Netherlands: epidemiology and genetic and molecular characterization of their plasmids.
Penicillinase-producing Neisseria gonorrhoeae strains were isolated in the Netherlands with increasing frequency during the period of 1976 to 1979. About 3% of the gonococci isolated in the first half of 1979 produced penicillinase. In contrast to the period of 1976 to 1977, most penicillinase-producing N. gonorrhoeae infections during the period of 1978 to 1979 were contracted in the Netherlan...
متن کاملPenicillinase-producing plasmid types in Neisseria gonorrhoeae clinical isolates from Australia.
Penicillinase-producing Neisseria gonorrhoeae (PPNG) carrying the blaTEM-135 gene is of particular concern, as it is considered a stepping stone toward resistance to extended-spectrum cephalosporins. Here, we sought to characterize plasmid types and the occurrence of the blaTEM-135 gene for N. gonorrhoeae clinical isolates from Australia. We found that blaTEM-135 was prevalent in Australian PPN...
متن کاملPreviously undescribed 6.6-kilobase R plasmid in penicillinase-producing Neisseria gonorrhoeae.
A penicillin-resistant Neisseria gonorrhoeae strain was isolated. The resistance was due to the production of TEM-1 beta-lactamase encoded by a plasmid. This 6.6-kilobase plasmid was compared with the previously known 7.4- and 5.3-kilobase penicillin R plasmids of N. gonorrhoeae.
متن کاملConjugative plasmids in Neisseria gonorrhoeae.
A conjugation system initially discovered in beta-lactamase-producing gonococci mobilized small non-selftransmissible R plasmids encoding beta-lactamase (penicillinase) production into other gonococci, Neisseria, and Escherichia coli. This conjugation system was mediated by a separate selftransmissible plasmid of 23.9 X 10(6) daltons, pFA2. Conjugative plasmids capable of mobilizing R plasmids ...
متن کاملCharacterization of a novel β-lactamase-producing plasmid in Neisseria gonorrhoeae: sequence analysis and molecular typing of host gonococci.
OBJECTIVES To determine the complete nucleotide sequence of the novel Johannesburg β-lactamase-encoding gonococcal plasmid (pEM1) and to determine the strain relatedness of Johannesburg plasmid-containing penicillinase-producing Neisseria gonorrhoeae (PPNG) by molecular typing. METHODS Eleven PPNG isolates containing the Johannesburg β-lactamase-encoding plasmid were previously identified amo...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 58 8 شماره
صفحات -
تاریخ انتشار 2014